During a significant 55% increase in chikungunya cases this year, the health department plans to perform genomic sequencing on samples to identify potential mutations. Uncommon symptoms, such as hyperpigmentation and neurological complications like brain or heart tissue inflammation, have surfaced. In response to the nearly 55% surge in cases of chikungunya fever this year compared to the previous year, the health department has opted to sequence the genomes of select positive samples as a precautionary measure against genetic mutations in the virus. State health officials stated on Tuesday that uncommon symptoms like hyperpigmentation and neurological issues were not recent discoveries but rather extremely rare occurrences. Dr. Mahendra Jagtap, the joint director of the vector control program, explained that these symptoms could manifest when a chikungunya patient is co-infected with dengue or Japanese encephalitis, as noted in guidelines released by the Centre last year. A rapid action team has been established by the state to investigate the reasons behind the rise in chikungunya cases, which have increased from 1,702 in 2023 to 2,643 in 2024. In Greater Mumbai, chikungunya cases have surged from minor numbers to 256 by September 7. The rapid action team has issued guidelines for municipal and local officials on collecting and sending samples to the National Institute of Virology and B J Medical College in Pune for further evaluation. The guidelines specify that two blood samples should be collected from patients exhibiting neurological symptoms such as paralysis and hyperpigmentation for analysis in Pune. The goal is to identify any other neurotropic viruses in chikungunya patients and conduct genomic sequencing, as explained by a senior state official. Dr. Rajesh Karyakarte from B J Medical College mentioned that genomic sequencing would be instrumental in identifying potential mutations.The doctor emphasized the importance of sequencing as soon as enough samples are collected, particularly from ICU patients or those with severe symptoms. Private hospitals in the city reported a significant increase in chikungunya cases this year, with some patients requiring hospitalization for up to 10 to 15 days due to high fever and neurological issues. Children have also been affected, with an eight-month-old boy being admitted to SRCC Children's Hospital in Haji Ali. Dr. Bhupendra Avasthi from Surya Children's Hospital mentioned that children born to chikungunya-positive mothers may exhibit hyperpigmentation, which is a well-known symptom of the disease.